Table 3.

Prediction of PiB PET amyloid deposition

	Model 1*	Model 2†	Model 3‡	Model 4§
PCC
Mediterranean diet	−0.017 (0.016)	−0.018 (0.017)	−0.011 (0.016)
Physical activity	−0.005 (0.003) p=0.106	−0.005 (0.003)	−0.005 (0.003) p=0.096
Intellectual activity	0.053 (0.053)	0.021 (0.052)	0.016 (0.051)
Plasma homocysteine	−0.013 (0.012)	−0.006 (0.012)		−0.010 (0.012)
Plasma cholesterol	−0.002 (0.001)	−0.001 (0.001)		−0.001 (0.001)
Body mass index	−0.004 (0.005)	−0.005 (0.005)		−0.006 (0.005)
QUICKI scores	−1.720 (1.550)	−2.155 (1.581)		−2.016 (1.575)
Hypertension	−0.048 (0.041)	−0.026 (0.037)		−0.019 (0.036)
PCC PiB uptake at baseline	0.094 (0.238)	0.194 (0.259)	0.156 (0.261)	0.232 (0.252)
Sex	0.020 (0.031)
APOE status	0.042 (0.029)
Age	0.007 (0.004)
Time to follow-up	0.000 (0.000)
Constant	0.394 (0.256)	0.465 (0.264) p=0.088	0.126 (0.028) p<0.001	0.447 (0.263) p=0.090
Frontal cortex
Mediterranean diet	−0.016 (0.011) p=0.104	−0.018 (0.011) p=0.102	−0.011 (0.011)
Physical activity	−0.000 (0.002)	−0.001 (0.002)	−0.001 (0.002)
Intellectual activity	0.050 (0.036)	0.031 (0.036)	0.019 (0.036)
Plasma homocysteine	−0.001 (0.008)	−0.001 (0.008)		−0.002 (0.008)
Plasma cholesterol	−0.001 (0.001)	−0.001 (0.001)		−0.001 (0.001)
Body mass index	−0.001 (0.003)	−0.001 (0.003)		−0.001 (0.003)
QUICKI scores	−1.293 (1.008)	−1.497 (1.012)		−1.184 (1.001)
Hypertension	−0.005 (0.029)	−0.005 (0.026)		0.001 (0.025)
Frontal PiB uptake at baseline	0.000 (0.143)	0.003 (0.145)	0.001 (0.144)	0.026 (0.140)
Sex	0.017 (0.019)
APOE status	0.033 (0.019) p=0.084
Age	0.000 (0.002)
Time to follow-up	−0.000 (0.000)
Constant	0.234 (0.167)	0.256 (0.168)	0.010 (0.018) p<0.001	0.208 (0.166)

See legend to table 2. Only significant and marginally significant p values are reported in the table.

APOE, apolipoprotein E; PCC, posterior cingulate cortex; QUICKI, Quantitative Insulin Sensitivity Check Index.