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. 2018 Nov 21;11:8227–8237. doi: 10.2147/OTT.S179844

Figure 2.

Figure 2

Knocking down PDL1 in SMMC7721 and Huh7 decreased icotinib’s proliferation-inhibitory sensitivity.

Notes: (A) mRNA and protein level were reduced after PDL1 siRNA interference; (B) IC50 decreased on SMMC7721 and Huh7 after PDL1 had been knocked down. **P<0.01, ***P<0.001.

Abbreviations: LV, lentivirus; NC, negative control.