Table 3.
Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
|
|
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HR (95% CI) | p-value | HR (95% CI) | p-value | |
Age, yr | 1.015 (0.996–1.034) | 0.126 | 1.022 (0.999–1.045) | 0.061 |
Female sex | 0.535 (0.318–0.901) | 0.019 | 0.537 (0.308–0.936) | 0.028 |
Etiology of liver cirrhosis | 0.092 | - | - | |
Concurrent HCC | 2.252 (1.519–3.338) | <0.001 | 2.102 (1.331–3.318) | 0.001 |
Liver transplantation | 0.234 (0.086–0.636) | 0.004 | 0.234 (0.080–0.684) | 0.008 |
GV type | 0.933 | - | - | |
GOV 2 | 0.953 (0.512–1.775) | 0.880 | ||
IGV 1 | 0.843 (0.430–1.652) | 0.618 | ||
IGV 2 | 1.117 (0.153–9.077) | 0.876 | ||
Presence of active bleeding | 1.669 (1.003–2.777) | 0.049 | 1.383 (0.781–2.446) | 0.266 |
Initial mean blood pressure | 0.999 (0.986–1.011) | 0.829 | ||
Initial hemoglobin | 0.895 (0.822–0.974) | 0.010 | ||
Time to intervention | 1.000 (0.996–1.003) | 0.790 | ||
Albumin, g/dL | 0.567 (0.410–0.783) | 0.001 | 0.570 (0.375–0.866) | 0.009 |
Creatinine, mg/dL | 1.058 (0.947–1.182) | 0.319 | - | - |
Total bilirubin, mg/dL | 1.049 (1.022–1.078) | <0.001 | 1.059 (1.021–1.099) | 0.002 |
Prothrombin time, INR | 1.812 (1.320–2.488) | <0.001 | 1.440 (0.893–2.322) | 0.135 |
Ascites | 0.042 | 0.203 | ||
Mild to moderate | 1.651 (1.016–2.683) | 0.043 | 1.408 (0.835–2.375) | 0.199 |
Severe | 1.850 (0.951–3.601) | 0.070 | 1.694 (0.817–3.510) | 0.156 |
Portosystemic encephalopathy | 0.933 | - | - | |
Mild to moderate | 1.147 (0.557–2.364) | 0.710 | ||
Severe | 1.021 (0.413–2.523) | 0.963 | ||
BRTO group | 0.601 (0.352–1.025) | 0.061 | 0.336 (0.178–0.633) | 0.001 |
HR, hazard ratio; CI, confidential interval; HCC, hepatocellular carcinoma; GV, gastric varices; INR, international normalized ratio; BRTO, balloon-occluded retrograde transvenous obliteration.