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. 2018 Nov 6;9(87):35762–35779. doi: 10.18632/oncotarget.26299

Table 1. Genes in P-glycoprotein-overexpressing CEM/ADR5000 cells those are consistent with PTEN activation after nimbolide treatment.

Gene symbol Exper. Fold change Gene symbol Exper. Fold change
MXD4 2.325 CXCR4 −1.095
KLHL24 1.800 FAS −1.115
NDRG1 1.720 CFD −1.185
MEF2D 1.290 CCND1 −1.185
AKR1C3 1.255 MAPKAPK3 −1.200
SAT1 1.215 PA2G4 −1.270
HSPA1A/HSPA1B 1.215 NOP2 −1.320
TOM1 1.175 SCD −1.345
IFRD1 1.170 VEGFB −1.515
BTG1 1.090 CDK4 −1.590
KLF6 1.005 ATP5MC1 −1.680
ACACA −1.010 MRPL12 −2.145
H2AFY −1.015 FASN −2.355
SREBF1 −1.025 MYC −4.260
SORD −1.065

IPA program highlighted 29 genes from the dataset that have measurement directions in consistence with PTEN activation (p-value 7.98 × 10−13).