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Cytotoxic effects of 1 and 2 on CCRF-CEM, HTB-54, HT-29, MCF-7 and 184B5 cells. Cells were incubated in the presence of each compound at the indicated concentration for 72 hours. Cytotoxicity was then determined by a colorimetric microassay based on the use of MTT. Data are expressed as percentage growth ± SEM from at least 3 independent experiments performed in quadruplicate.
