Table 7.

Cytotoxic activities (average GI₅₀^a, TGI^b and LD₅₀^c values) for compounds against tumour cell lines.

Comp.	C.Pa (μM)	Cell lines
		CCRF-CEM	HTB-54	HT-29	MCF-7	184B5
1	bGI50	>100	0.58	7.39	0.09	1.97
	cTGI	>100	42.47	55.98	3.69	22.50
	dLD50	>100	>100	>100	58.01	76.73
2	GI50	>100	1.90	8.95	2.64	2.29
	TGI	>100	9.91	51.95	6.54	20.14
	LD50	>100	>100	>100	23.12	78.91
11	GI50	>100	11.14	16.19	0.006	1.05
	TGI	>100	>100	72.19	4.18	9.64
	LD50	>100	>100	>100	53.49	72.34
14	GI50	>100	16.82	5.99	1.57	0.0009
	TGI	>100	>100	47.42	6.19	8.21
	LD50	>100	>100	>100	52.65	62.55
21	GI50	>100	11.79	7.53	0.003	0.05
	TGI	>100	>100	60.94	8.27	1.89
	LD50	>100	>100	>100	89.21	7.20
Doxorub.	GI50	0.033	<0.01	nde	0.88	nd
	TGI	0.071	1.25	nd	>100	nd
	LD50	0.29	3.45	nd	>100	nd

^a Cytotoxic parameters; ^b Dose that inhibits 50% of cell growth; ^c Dose that completely inhibits cell growth; ^d Dose that kills 50% of cells; ^e n.d.: not determined.