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Expression of SphK1, FAK and p-FAK in tissues assessed by immunohistochemistry staining.
| Colonic samples | n | SphK1
|
FAK
|
p-FAK
|
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| − | + | P-value | − | + | P-value | − | + | P-value | ||
| Normal colonic mucosa tissues | 50 | 44 | 6 | 0.001 | 40 | 10 | 0.001 | 43 | 7 | 0.001 |
| Non-metastatic cancer tissues | 63 | 27 | 36 | 29 | 34 | 37 | 26 | |||
| Metastatic cancer tissues | 51 | 9 | 42 | 6 | 45 | 13 | 38 | |||
SphK1, Sphingosine kinase 1; FAK, focal adhesion kinase; p, phosphorylated.
