Table 1.
Inhibitory rates (%) against HL-60.
| Compounds | Concentration (mol/L) | ||||
|---|---|---|---|---|---|
| 10−4 | 10−5 | 10−6 | 10−7 | 10−8 | |
| 2a | 2.0 | 8.0 | 9,6 | 6.9 | 8.3 |
| 2b | 3.7 | 5.2 | 6.2 | 9.7 | 2.8 |
| 2c | 33.1 | 0.1 | 9.9 | 9.8 | 0 |
| 2d | 27.3 | 0 | 1.7 | 0 | 10.0 |
| 2e-1 | 22.4 | 11.2 | 7.1 | 4.2 | 1.2 |
| 2e-2 | 18.5 | 15.3 | 3.4 | 10.5 | 0 |
| 2f-1 | 3.3 | 10.8 | 6.6 | 12.3 | 0 |
| 2f-2 | 31.8 | 9.2 | 3.7 | 6.2 | 0 |
| 2g | 36.1 | 10.0 | 5.7 | 5.0 | 2.5 |
| 2h | 55.7 | 19.6 | 23.1 | 2.3 | 8.6 |
| 2i | 2.8 | 6.7 | 1.5 | 8.3 | 0.6 |
| 2j | 55.8 | 12.8 | 2.7 | 5.4 | 5.9 |
| 2k-1 | 29.2 | 0 | 3.8 | 8.2 | 2.4 |
| 2k-2 | 51.2 | 15.5 | 9.8 | 12.7 | 8.9 |
| 2l | 42.4 | 7.9 | 5.2 | 9.9 | 5.7 |
| 2m | 65.1 | 0 | 12.6 | 13.0 | 0.3 |
| 2n | 11.4 | 0 | 0 | 0 | 0 |
| 2o | 22.4 | 11.2 | 7.1 | 4.2 | 1.2 |
| 5-FU | 57.4 | 33.5 | 0 | 7.0 | 10.4 |
| FT-207 | 0 | 0 | 0 | 0 | 0 |