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. 2009 Nov 4;14(11):4425–4432. doi: 10.3390/molecules14114425

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© 2009 by the authors;

licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

PMC Copyright notice

Effect of catechins (EGCG, EGC and C) and GA on melanin production. The melanin content of B16 melanoma cells was measure after 5 days of treatment with or without test substances, as described in the Experimental. Results are expressed as pg/cell, and average of melanin contents per cell of control groups were 113.5 pg/cell (EGCG), 109.4 pg/cell (EGC), 115.3 (C) and 117.4 pg/cell (GA). Data reported are the means ± S.D. of at least three separate experiments. *P < 0.05 and **P < 0.01 versus control (α-MSH alone treated) group. † P < 0.01 versus media only treated group.