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Effects of Vorinostat on raft cultures of W12-E cells (A) and CaSki cells (B). Day 14 cultures were exposed to DMSO (Left) or 1 (Middle) or 5 μM (Right) Vorinostat from days (A) 6 to 14 or (B) 5 to 14. Rows are as follows: (A) histology (Upper), BrdU incorporation (Middle), and γ-H2AX and TUNEL (Lower) signals; (B) histology (Upper) and TUNEL (Lower) signals.
