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. 2009 Dec 9;14(12):5124–5143. doi: 10.3390/molecules14125124

Table 1.

Synthesis of azido alcohols.

graphic file with name molecules-14-05124-i001.jpg

Compound R1 R2 Yield (%)
5 H CH2Ph -
6 CH2Ph H -
7 H CH2CH2Ph -
8 H CH(CH3)2 -
9 H CH2OCH2Ph -
10 H CH2Ph 79
11 CH2Ph H 91
12 H CH2CH2Ph 92
13 H CH(CH3)2 96
14 H CH2OCH2Ph 97
15 H CH2Ph 76
16 CH2Ph H 72
17 H CH2CH2Ph 74
18 H CH(CH3)2 70
19 H CH2OCH2Ph 73

(i) LiAlH4, THF, 16 h, reflux. (ii) TfN3, DMAP, DCM, 15 h, RT.