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Synthesis of dilactone 15.
Reagents and conditions: a) PCC, CH2Cl2, 12h, 65% b) allylmagnesium bromide, 0ºC, 3h, 43%c) Acryloyl chloride, DIPEA, CH2Cl2, 0ºC, 64% d) first generation Grubbs ruthenium catalyst, CH2Cl2, 60ºC, giving dilactone 15 and the corresponding dimer, in 65% yield (80:20 ratio).
