Table 1.
Antimicrobial activity* of P. debilis.
| Compound a,b,c | Microorganism | MIC e (µg/mL) |
|---|---|---|
| PC | C. diphtheriae NCTC 10356, B. subtilis ATCC 6633, | 256 |
| B. cereus, B. catarrhalis, P. shigelloides | ||
| PE | C. diphtheriae NCTC 10356, B. subtilis ATCC 6633, | 256 |
| B. cereus | ||
| C2 | B. subtilis ATCC 6633 | 256 |
| C3 | C. diphtheriae NCTC 10356, | 64 |
| B. subtilis ATCC 6633, B. catarrhalis | 128 | |
| M. lutens ATCC 10240, B. cereus, P. shigelloides, M. flavas | 256 | |
| C4 | C. diphtheriae NCTC 10356, B. subtilis ATCC 6633 | 256 |
| C5 | C. diphtheriae NCTC 10356, B. subtilis ATCC 6633 | 128 |
| B. cereus | 256 | |
| C7d | C. diphtheriae NCTC 10356, B. subtilis ATCC 6633, | 64 |
| B. cereus, B. catarrhalis, P. shigelloides | ||
| S. pyogenes | 256 | |
| C8d | C. diphtheriae NCTC 10356, B. subtilis ATCC 6633, | 64 |
| M. lutens ATCC 10240, B. cereus, B. catarrhalis, P. shigelloides, S. pyogenes | ||
| S. aureus ATCC 25923, S. epidermidis ATCC 12228, | 256 | |
| E. faecalis ATCC 29212, M. flavas, E. tarda, N. mucosa, L. monocytogenes | ||
| C9d | C. diphtheriae NCTC 10356, B. subtilis ATCC 6633, B. cereus, B. catarrhalis | 64 |
| P. shigelloides | 128 | |
| M. lutens ATCC 10240, S. epidermidis ATCC 12228, E. faecalis ATCC 29212, E. tarda | 256 | |
| E3.6 | C. diphtheriae NCTC 10356 | 256 |
| E4 | C. diphtheriae NCTC 10356, B. subtilis ATCC 6633, B. cereus, B. catarrhalis, P. shigelloides | 256 |
Partial inhibition at 256 μg/mL: a C6 against C. diphtheriae NCTC 10356 (50%), S. pyogenes (75%); b C8 against C. albicans (75%); c E5 against C. diphtheriae NCTC 10356 and B. subtilis ATCC 6633 (50%). *Ampicillin at 10 μg/mL showed complete inhibition against S. aureus ATCC 25923, S. epidermidis ATCC 12228, B. subtilis ATCC 6633, N. mucosa, B. catarrhalis, E. tarda and S. pyogenes. d Fractions contained a mixture of triterpenoids. e minimum inhibitory concentration.