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. 2018 Nov 26;8:17345. doi: 10.1038/s41598-018-35559-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Flow cytometric analysis of apoptosis induction. Effect of α-Lac, DOX, PTX, α-Lac:DOX, and α-Lac:PTX on apoptosis induction in MDA-MB-231 cells after incubation for 48 h. The cells were incubated with 1 (b) and 2 (c) μM α-Lac, 2 µM DOX (d), 1:2 ratio of α-Lac:DOX (e), 2:2 ratio of α-Lac:DOX (f), 2 μM PTX (g), 1:2 ratio of α-Lac:PTX (h), and 2:2 ratio of α-Lac:PTX (i). The presented graphs are representative of the flow cytometric output. The control cells were also presented to compare (a).