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. 2018 Nov 6;175(24):4496–4506. doi: 10.1111/bph.14504

Figure 1.

Figure 1

Displacement of [3H]‐N/OFQ in CHOhNOP cell membranes by a range of concentrations of N/OFQ and N/OFQATTO594 (A). Displacement of [3H]‐DPN in CHOhμ cell membranes by a range of concentrations of dermorphin and N/OFQATTO594 (B). Displacement of [3H]‐DPN in CHOhκ cell membranes by a range of concentrations of dynorphin‐A and N/OFQATTO594 (C). Displacement of [3H]‐DPN in CHOhδ cell membranes by a range of concentrations of Leu‐enkephalin and N/OFQATTO594 (D). Displacement binding affinities for N/OFQATTO594 and control ligands are summarised in the table (NOP: N/OFQ; μ: dermorphin; δ: Leu‐enkephalin; κ: dynorphin‐A). Data are the mean ± SEM of five experiments.