Table 2.
Description of key pathways involved in the cross-talk network.
| Pathways | Functional class | KO path | # of genes | Mean e-value | Mean % identity |
|---|---|---|---|---|---|
| Arganine and proline metabolism | Amino acid metabolism | ko00330 | 11 | 0.0 | 92.0 |
| Ascorbate and aldarate metabolism | Amino acid metabolism | ko00053 | 6 | 0.0 | 93.2 |
| Cysteine and methionine metabolism | Amino acid metabolism | ko00270 | 4 | 0.0 | 93.1 |
| Glycine, serine and threonine metabolism | Amino acid metabolism | ko00260 | 9 | 0.0 | 95.0 |
| Histidine metabolism | Amino acid metabolism | ko00340 | 6 | 0.0 | 98.1 |
| Lysine degradation | Amino acid metabolism | ko00310 | 5 | 0.0 | 92.7 |
| Phenylalanine metabolism | Amino acid metabolism | ko00360 | 3 | 0.0 | 86.0 |
| Tryptophane metabolism | Amino acid metabolism | ko00380 | 5 | 0.0 | 93.3 |
| Tyrosine metabolism | Amino acid metabolism | ko00350 | 10 | 0.0 | 93.1 |
| Valine, leucine and isoleucine degradation | Amino acid metabolism | ko00280 | 5 | 0.0 | 92.7 |
| Carbapenem biosynthesis | Biosynthesis of other secondary metabolites | ko00332 | 4 | 0.0 | 95.0 |
| Phenylpropanoid biosynthesis | Biosynthesis of other secondary metabolites | ko00940 | 5 | 0.0 | 92.8 |
| Amino sugar and nucleotide sugar metabolism | Carbohydrate metabolism | ko00520 | 4 | 0.0 | 91.2 |
| Galactose metabolism | Carbohydrate metabolism | ko00052 | 5 | 0.0 | 91.2 |
| Glycolysis/Gluconeogenesis | Carbohydrate metabolism | ko00010 | 17 | 0.0 | 94.8 |
| Glyoxylate and decarboxylate metabolism | Carbohydrate metabolism | ko00630 | 4 | 0.0 | 95.4 |
| Pentose and glucuronate interconversion | Carbohydrate metabolism | ko00040 | 6 | 0.0 | 93.1 |
| Pentose phosphate pathway | Carbohydrate metabolism | ko00030 | 5 | 0.0 | 96.3 |
| Pyruvate metabolism | Carbohydrate metabolism | ko00620 | 8 | 0.0 | 94.2 |
| Starch and sucrose metabolism | Carbohydrate metabolism | ko00500 | 10 | 0.0 | 95.2 |
| Methane metabolism | Carbon metabolism | ko01200 | 4 | 0.0 | 94.3 |
| Carbon fixation in photosynthetic organisms | Energy metabolism | ko00710 | 9 | 0.0 | 92.9 |
| Oxidative phosphorylation | Energy metabolism | ko00190 | 7 | 0.0 | 93.7 |
| mTOR signaling pathway | Environmental Information Processing; Signal transduction | ko04150 | 4 | 0.0 | 95.8 |
| Alpha-Linolenic acid metabolism | Lipid metabolism | ko00592 | 7 | 0.0 | 96.1 |
| Fatty acid degradation | Lipid metabolism | ko00071 | 11 | 0.0 | 94.5 |
| Pantotenate and CoA biosynthesis | Metabolism of cofactors and vitamins | ko00770 | 3 | 0.0 | 92.9 |
| Retinol metabolism | Metabolism of cofactors and vitamins | ko00830 | 6 | 0.0 | 95.8 |
| Beta-alanine metabolism | Metabolism of other amino acids | ko00410 | 4 | 0.0 | 92.9 |
| Glutathione metabolism | Metabolism of other amino acids | ko00480 | 10 | 0.0 | 87.6 |
| Glycerolipid metabolism | Metabolism of other amino acids | ko00561 | 6 | 0.0 | 91.3 |
| Biosynthesis of antibiotics | Metabolism of terpenoids and polyketides | ko01130 | 28 | 0.0 | 93.5 |
| Carotenoid biosynthesis | Metabolism of terpenoids and polyketides | ko00906 | 5 | 0.0 | 90.9 |
| Limonene and pinene degradation | Metabolism of terpenoids and polyketides | ko00903 | 5 | 0.0 | 92.7 |
| Purine metabolism | Nucleotide metabolism | ko00230 | 6 | 0.0 | 89.4 |
| Pyrimidine metabolism | Nucleotide metabolism | ko00240 | 3 | 0.0 | 92.0 |
| Chloroalkane and chloroalkene degradation | Xenobiotics biodegradation and metabolism | ko00625 | 11 | 0.0 | 94.5 |
| Drug metabolism—other enzymes | Xenobiotics biodegradation and metabolism | ko00983 | 4 | 0.0 | 90.3 |
| Drug metabolism Cytochrome p450 | Xenobiotics biodegradation and metabolism | ko00982 | 15 | 0.0 | 89.4 |
| Metabolism of xenobiotics by cytochrome p450 | Xenobiotics biodegradation and metabolism | ko00980 | 12 | 0.0 | 96.6 |
| Naphtalene degradation | Xenobiotics biodegradation and metabolism | ko00626 | 5 | 0.0 | 94.7 |