Table 3.
Baseline mean ± SD for vertigo parameters for the overall populations in the MAD studies
| Day 4 (n = 36) | Day 7 (n = 24) | |
|---|---|---|
| Latency of vertigo appearance (s) | 32.8 ± 15.4 | 32.2 ± 8.5 |
| Latency of vertigo disappearance (s) | 150.3 ± 24.7 | 141.9 ± 46.4 |
| Duration of the vertigo (s) | 117.5 ± 29.2 | 109.6 ± 45.1 |
| Intensity sensation VAS (mm) | 57.8 ± 18.3 | 54.7 ± 24.0 |
| Illusion of movement, 2/3/4, n (%) a | 9 (25.0) /10 (27.8) /17 (47.2) | 7 (29.2) /7 (29.2) /10 (41.7) |
| Duration of illusion, <1 min/ ≥1 min −1 h −1 , n (%) | 20 (55.6) /16 (44.4) | 12(50.0) /12 (50.0) |
| Motion intolerance, 0/1/2/3 b | 18 (50.0) /11 (30.6) /6 (16.7) /1 (2.8) | 16 (66.7) /3 (12.5) /4 (16.7) /1 (4.2) |
| Neurovegetative signs, 0/1/2 c , n (%) | 30 (83.3) /4 (11.1) / 2(5.6) | 24 (100.0) /0/0 |
| Instability, 0/1/2/3 d , n (%) | 23(63.9) /12(33.3) /1(2.8) | 17(70.8) /6(25.0) /0/1(4.2) |
| Total EEV score (0 to 20) | 5.9 ± 2.0 | 5.6 ± 2.0 |
a
2 = Feeling of swaying to the right or left; 4 = Impression of spinning
b
0 = No motion intolerance; 1 = Rarely or few; 2 = Sometimes or moderate; 3 = Often or marked
c
0 = No signs; 1 = Nausea uncorrelated with attacks of vertigo; 2 = Nausea correlated with attacks of vertigo
d
0 = No instability; 1 = Instability but no falls and no interference with daily activity; 2 = Instability without falls, but interferences with daily activity; 3 = Instability with occasional falls