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. 2018 Nov 20;9:1312. doi: 10.3389/fphar.2018.01312

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Copyright © 2018 Zhao, Huang, Shi, Dai, Wu and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of ABCC10 on cell apoptosis of gefitinib-sensitive and -resistant NSCLC cells after gefitinib exposure. (A,C) Influence of ABCC10 overexpression on cell apoptosis of gefitinib-sensitive PC9 and H292 cells treated with 1 μmol/L gefitinib for 72 h. (B,D) Influence of ABCC10 knockdown on cell apoptosis of gefitinib-resistant PC9/GR and H292/GR cells treated with 1 μmol/L gefitinib for 72 h. *P < 0.05, **P < 0.01 compared to the empty-vector-transfected cells (EV) or shMock-transfected cells (shMock).