Table 1.
Identification of SNPs in genome of Lactobacillus rhamnosus GG KCTC 5033 compared with that of L. rhamnosus GG ATCC 53103 as the reference genome.
| No | Start | End | Strand | Mutation Position | Reference sequence | Altered sequence | Amino acid change | Enzyme |
|---|---|---|---|---|---|---|---|---|
| 1 | 263021 | 264508 | ++ | 264278 | G | A | Ala→Thr | MFS transporter |
| 2 | 614219 | 616219 | + | 615483 | T | C | Leu→Pro | PTS beta-glucoside transporter subunit IIABC |
| 3 | 655200 | 657050 | - | 656560 | ACGCCGCC | ACGCCGCCGCC | QGGV→ QGGGV | alpha-glycerophosphate oxidase |
| 4 | Intergenic space | / | 751602 | G | A | / | / | |
| 5 | Intergenic space | / | 751632 | T | G | / | / | |
| 6 | Intergenic space | / | 751633 | T | C | / | / | |
| 7 | Intergenic space | / | 751663 | T | C | / | / | |
| 8 | 876317 | 876952 | - | 876397 | TGCCGCCG | TGCCGCCGCCG | LPGGI→ LPAGGI | Copper homeostasis protein CutC |
| 9 | Intergenic space | / | 1154682 | T | G | / | / | |
| 10 | 1370968 | 1372521 | + | 1372183 | T | A | Leu→Met | 2′, 3′-cyclic nucleotide 2′-phosphodiesterase |
| 11 | Intergenic space | / | 1873061 | CGG | CG | / | / | |
| 12 | Intergenic space | / | 1873072 | G | T | / | / | |
| 13 | Intergenic space | / | 1873075 | C | G | / | / | |
| 14 | Intergenic space | / | 1873076 | T | C | / | / | |
| 15 | Intergenic space | / | 1873089 | G | A | / | / | |
| 16 | Intergenic space | / | 1873091 | T | C | / | / | |
| 17 | Intergenic space | / | 1873092 | G | A | / | / | |
| 18 | Intergenic space | / | 1873879 | T | C | / | / | |
| 19 | Intergenic space | / | 1883242 | C | A | / | / | |
| 20 | 1993822 | 1997424 | - | 1994717 | T | A | Asp→Val | peptidoglycan-binding protein LysM |
| 21 | 2158636 | 2160858 | + | 2158707 | C | T | X | BREX-1 system adenine-specific DNA-methyltransferase |
| 22 | 2158636 | 2160858 | + | 2158710 | G | A | X | |
| 23 | 2158636 | 2160858 | + | 2158719 | C | T | X | |
| 24 | 2161973 | 2165527 | - | 2164868 | T | C | X | BREX-1 system adenine-specific DNA-methyltransferase |
| 25 | 2161973 | 2165527 | - | 2164871 | A | G | X | |
| 26 | 2351546 | 2355847 | - | 2352806 | G | A | X | Cell surface protein |
| 27 | 2351546 | 2355847 | - | 2352965 | A | T | X | |
| 28 | 2351546 | 2355847 | - | 2353053 | A | G | Val→Ala | |
| 29 | 2351546 | 2355847 | - | 2353148 | T | C | X | |
| 30 | 2351546 | 2355847 | - | 2353155 | T | C | Gln→Arg | |
| 31 | 2351546 | 2355847 | - | 2353178 | G | A | X | |
| 32 | 2351546 | 2355847 | - | 2353217 | A | G | X | |
| 33 | 2351546 | 2355847 | - | 2353220 | A | T | X | |
| 34 | 2351546 | 2355847 | - | 2353382 | G | A | X | |
| 35 | 2351546 | 2355847 | - | 2353391 | C | T | X | |
| 36 | 2351546 | 2355847 | - | 2353466 | G | A | X | |
| 37 | 2351546 | 2355847 | - | 2353548 | G | A | Ser→Phe | |
| 38 | 2351546 | 2355847 | - | 2353713 | A | G | Val→Ala | |
| 39 | 2452189 | 2453244 | + | 2452317 | A | G | X | Hypothetical protein |
| 40 | 2574214 | 2574357 | + | 2574344 | A | G | Glu→Gly | Malolactic regulator |
| 41 | 2574214 | 2574357 | + | 2574345 | A | G | X | |