Table 2.
Genetic mutations identified in FTG-evolved L. rhamnosus GG clones.
| Position (bp) | Gene or region | Gene description | Mutation | Identification of mutation |
|
|---|---|---|---|---|---|
| LR 1 | LR 2 | ||||
| 256855 | LGG_RS01240 (dacA) | D-Alanyl-D-alanine carboxypeptidase | Insertion (position 903, +A) | × | ○ |
| 1272968 | LGG_RS06120 (cls) | Cardiolipin synthase | Missense | ○ | × |
| 1473969 | LGG_RS07040 (cls) | × | ○ | ||
| 2106059 | LGG_RS09880 (wze) | Exopolysaccharide biosynthesis protein | Missense | × | ○ |
| 2106381 | ○ | × | |||
| 2160010 | LGG_RS10085 (pglX) | BREX-1 system adenine-specific DNA-methyltransferase | Missense | ○ | ○ |
| 2163622 | LGG_RS10095 (pglX) | ○ | ○ | ||
| 2192576 | LGG_RS10195 (fabK) | 2-nitropropane dioxygenase | Missense | ○ | ○ |
| 2844194 | LGG_RS13275 (murQ) | N-acetylmuramic acid-6-phosphate etherase | Missense | × | ○ |
| 1551606 | LGG_RS07350← / ←LGG_RS07355 | Intergenic space | Intergenic mutation (-117/+365, G to T) | ○ | ○ |