Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Synthesis of N-cyclopentyl series. (i) piperazine, N,N-diisopropylethylamine, THF, reflux, 12 h, 48%; (ii) tert-butyl N-(6-bromohexyl) carbamate or tert-butyl N-{2-[2-(2-bromoethoxy)ethoxy]ethyl}carbamate, K2CO3, NaI, dioxane, reflux, 24 h, 66–72%; and (iii) CH2Cl2, trifluoroacetic acid, 78–96%.
