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. 2018 Nov 20;9:965. doi: 10.3389/fneur.2018.00965

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Copyright © 2018 Li, Li, Chopp, Venkat, Zacharek, Chen, Landschoot-Ward, Yan and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ICH significantly increases cardiac inflammatory cell infiltration compared to sham control mice. ICH increases cardiac inflammatory cells infiltration at 7 days after ICH. (A) CD45 (leukocyte marker) and (B) IBA1 (macrophage marker) immunostaining and quantitative data at 7 days after ICH. ICH in mice significantly increases (C) M1 macrophage indicated by CD86 and (D) M2 macrophage indicated by CD206 in heart compared to sham control mice. (A,B) scale bar, 50 μm; (C,D) scale bar, 20 μm. Data are presented as mean ± SE. ^*p < 0.05 compared with sham.