Table II.
Results of unvariate and multivariate analysis influencing OS.
| Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
| Variables | No. (%) | P-value | HR | 95% CI | P-value |
| Age, years | |||||
| ≤75 | 9 (20) | 0.808 | |||
| >75 | 36 (80) | ||||
| PS | |||||
| 1, 2 | 7 (15.6) | <0.001 | |||
| 0 | 38 (84.4) | ||||
| Visceral metastasis | |||||
| Yes | 13 (28.9) | 0.036 | 2.926 | 1.196–7.157 | 0.019 |
| No | 32 (71.1) | ||||
| PSA (ng/ml) | |||||
| >100 | 23 (51.1) | 0.002 | 4.375 | 1.755–10.91 | 0.002 |
| ≤100 | 22 (48.9) | ||||
| Hb (mg/dl) | |||||
| ≤11 | 18 (40) | <0.001 | |||
| >11 | 27 (60) | ||||
| AMC (/µl) | |||||
| <400 | 25 (55.6) | 0.026 | 2.955 | 1.219–7.165 | 0.017 |
| ≥400 | 20 (44.4) | ||||
| NLR | |||||
| ≥4.3 | 23 (51.1) | 0.097 | |||
| <4.3 | 22 (48.9) | ||||
| ALP (IU/l) | |||||
| >350 | 17 (37.8) | 0.268 | |||
| ≤350 | 28 (62.2) | ||||
ECOG PS, Eastern Cooperative Oncology Group ECOG performance status; PSA, prostate-specific antigen; Hb, hemoglobin; AMC, absolute monocyte count; NLR, Neutrophil to Lynphocyte ratio; ALP, alkaline Phosphatase.