Table 3.
Regression analyses between inflammatory agents and dimensions of depression.
| BDI-II sum score | Somatic-affective dimension | Cognitive dimension | |
|---|---|---|---|
| logCRP | 6.109 (−6.737 to 18.955) = 0.350 | 3.574 (−3.663 to 10.811) = 0.331 | 1.788 (−3.795 to 7.370) = 0.528 |
| logTNF-α | 9.212 (3.017 to 15.408) = 0.004* | 6.011 (2.528 to 9.494),<0.001* | 3.849 (1.116 to 6.582) = 0.006* |
| logIFN-γ | 15.517 (10.463 to 20.571),<0.001* | 8.723 (5.854 to 11.593),<0.001* | 5.939 (3.697 to 8.180),<0.001* |
| logIL-2 | 1.974 (−1.107 to 5.056) = 0.208 | 1.160 (−0.576–2.897) = 0.189 | 0.956 (−0.383 to 2.294) = 0.161 |
| logIL-4 | 3.219 (−4.954 to 11.392) = 0.438 | 2.216 (−2.425 to 6.858) = 0.348 | 1.801 (−1.753 to 5.354) = 0.319 |
| logIL-5 | 9.248 (4.664 to 13.832),<0.001* | 5.904 (3.341 to 8.468),<0.001* | 3.244 (1.228 to 5.260) = 0.002* |
| logIL-10 | 3.437 (−0.445 to 7.318) = 0.082 | 1.998 (−0.193 to 4.190) = 0.074 | 1.387 (−0.300 to 3.074) = 0.107 |
| logIL-12 | 6.743 (3.647 to 9.839),<0.001* | 3.872 (2.118 to 5.626),<0.001* | 3.108 (1.749 to 4.466),<0.001* |
| logIL-13 | 6.370 (1.900 to 10.840) = 0.005* | 3.904 (1.388 to 6.420) = 0.003* | 2.860 (0.897 to 4.823) = 0.005* |
| logGM-CSF | 5.531 (0.119 to 10.944) = 0.045 | 3.198 (0.150 to 6.246) = 0.040 | 2.839 (0.491 to 5.187) = 0.018* |
Coefficient (95%-CI), p-value. Significant correlations are highlighted in bold font. Significance after correction for multiple comparisons is labeled with an asterisk.