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. 2018 Oct 3;16(6):7223–7230. doi: 10.3892/ol.2018.9542

Figure 2.

Figure 2.

(A) Correlation between expression of RASEF mRNA and conventional biomarkers. RASEF mRNA levels were significantly lower in ER-negative, PgR-negative, and triple-negative specimens than in ER-positive, PgR-positive, and non-triple-negative specimens. (B) Comparison of RASEF mRNA levels among ER-positive/PgR-positive, ER-positive/PgR-negative, and ER-negative/PgR-negative groups. ER-negative/PgR-negative specimens exhibited significantly lower RASEF mRNA expression than ER-positive/PgR-positive specimens. *P<0.001. RASEF, RAS and EF-hand domain-containing; N.S, not significant; ER, estrogen receptor; PgR, progesterone receptor; HER2, human epidermal growth factor 2.