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Downregulation of HDAC6 was detected in HCC cell lines and tissues. (A) Expression of HDAC6 in the HCC cell lines Hep3B and Huh-7, and the normal liver cell line Lo2 detected using western blot analysis. (B) Protein expression of HDAC6 observed in HCC tissues (magnification, ×200) and carcinoma-adjacent tissues, detected using immunohistochemical staining. HCC, hepatocellular carcinoma; HDAC6, histone deacetylase 6.
