Table I.
Characteristics of all participants.
| Characteristics | HCC (n=84) | Liver cirrhosis (n=74) | Chronic hepatitis (n=29) | Healthy control (n=30) |
|---|---|---|---|---|
| Age, years, mean (range) | 57 (33–78) | 55 (31–75) | 36 (23–57) | 32 (28–40) |
| Sex, n | ||||
| Male | 69 | 42 | 14 | 14 |
| Female | 15 | 32 | 15 | 16 |
| Etiology, n | ||||
| HBV infection | 71 | 41 | 17 | 0 |
| HCV infection | 13 | 33 | 12 | 0 |
| ALT, U/l, mean ± SD | 65.80±61.09 | 75.80±101.80 | 57.48±59.68 | 26.23±6.48a,b |
| AST, U/l, mean ± SD | 98.70±86.37 | 92.04±119.67 | 49.21±39.07a,b | 25.37±9.13a,b |
| Albumin, g/l, mean ± SD | 32.82±6.03 | 33.52±6.79 | 41.04±4.56a,b | 39.81±3.75a,b |
| TBil, µmol/l, mean ± SD | 59.19±90.31 | 47.23±74.16 | 14.38±5.35a,b | 11.50±3.96a,b |
| PT INR | 1.15±0.18 | 1.16±0.27 | 0.98±0.09a,b | 0.93±0.09a,b |
a
P<0.05 vs. patients with HCC.
b
P<0.05 vs. patients with liver cirrhosis. HCC, hepatocellular carcinoma; HBV, hepatitis B virus; HCV, hepatitis C virus; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBil, total bilirubin; PT INR, prothrombin time international normalized ratio; SD, standard deviation.