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. 2018 Sep 25;9(11):1949–1960. doi: 10.1039/c8md00464a

Table 2. In vitro cancer cell growth inhibiting rate of compound (5 μM) alone.

Compound (5 μM) Inhibition rate (% of control)
A549 HepG2 KB MCF-7 HeLa HCT116
6a 8.17 ± 0.50 5.46 ± 0.22 4.38 ± 2.73 1.38 ± 0.65 8.58 ± 0.34 8.60 ± 2.16
6b 9.26 ± 1.42
6c 6.76 ± 2.01 3.49 ± 0.30 2.16 ± 0.81 2.35 ± 0.35 7.08 ± 0.04 5.61 ± 1.32
6d 11.34 ± 3.27
6e 7.92 ± 2.15 13.20 ± 1.76 3.70 ± 0.81 1.86 ± 0.36 1.49 ± 0.48 20.35 ± 1.25
6f 23.77 ± 0.21 11.25 ± 3.26 2.15 ± 2.10 0.86 ± 0.10 1.07 ± 0.57 16.38 ± 1.25
6g 3.11 ± 0.15 9.45 ± 2.84 2.55 ± 3.38 3.78 ± 0.50 8.47 ± 1.71 14.86 ± 2.89
6h 6.69 ± 0.67 6.90 ± 1.65 0.43 ± 0.60 6.26 ± 0.30 10.45 ± 0.34 20.44 ± 1.46
10a 15.86 ± 1.02
10b 7.60 ± 0.99 11.51 ± 4.45 7.35 ± 0.81 4.65 ± 3.23 4.80 ± 0.58 17.86 ± 2.56
10c 1.44 ± 0.85 5.10 ± 1.20 2.15 ± 1.06 11.95 ± 0.42 3.55 ± 1.58 12.29 ± 2.97
13a 11.09 ± 0.24
13b 10.93 ± 2.17
13c 12.56 ± 1.84
Cisplatin 39.77 ± 1.01 55.09 ± 3.21 24.30 ± 3.29 7.76 ± 1.35 34.99 ± 0.16 41.12 ± 0.39