Table 2. In vitro cancer cell growth inhibiting rate of compound (5 μM) alone.
| Compound (5 μM) | Inhibition rate (% of control) |
|||||
| A549 | HepG2 | KB | MCF-7 | HeLa | HCT116 | |
| 6a | 8.17 ± 0.50 | 5.46 ± 0.22 | 4.38 ± 2.73 | 1.38 ± 0.65 | 8.58 ± 0.34 | 8.60 ± 2.16 |
| 6b | — | — | — | — | — | 9.26 ± 1.42 |
| 6c | 6.76 ± 2.01 | 3.49 ± 0.30 | 2.16 ± 0.81 | 2.35 ± 0.35 | 7.08 ± 0.04 | 5.61 ± 1.32 |
| 6d | — | — | — | — | — | 11.34 ± 3.27 |
| 6e | 7.92 ± 2.15 | 13.20 ± 1.76 | 3.70 ± 0.81 | 1.86 ± 0.36 | 1.49 ± 0.48 | 20.35 ± 1.25 |
| 6f | 23.77 ± 0.21 | 11.25 ± 3.26 | 2.15 ± 2.10 | 0.86 ± 0.10 | 1.07 ± 0.57 | 16.38 ± 1.25 |
| 6g | 3.11 ± 0.15 | 9.45 ± 2.84 | 2.55 ± 3.38 | 3.78 ± 0.50 | 8.47 ± 1.71 | 14.86 ± 2.89 |
| 6h | 6.69 ± 0.67 | 6.90 ± 1.65 | 0.43 ± 0.60 | 6.26 ± 0.30 | 10.45 ± 0.34 | 20.44 ± 1.46 |
| 10a | — | — | — | — | — | 15.86 ± 1.02 |
| 10b | 7.60 ± 0.99 | 11.51 ± 4.45 | 7.35 ± 0.81 | 4.65 ± 3.23 | 4.80 ± 0.58 | 17.86 ± 2.56 |
| 10c | 1.44 ± 0.85 | 5.10 ± 1.20 | 2.15 ± 1.06 | 11.95 ± 0.42 | 3.55 ± 1.58 | 12.29 ± 2.97 |
| 13a | — | — | — | — | — | 11.09 ± 0.24 |
| 13b | — | — | — | — | — | 10.93 ± 2.17 |
| 13c | — | — | — | — | — | 12.56 ± 1.84 |
| Cisplatin | 39.77 ± 1.01 | 55.09 ± 3.21 | 24.30 ± 3.29 | 7.76 ± 1.35 | 34.99 ± 0.16 | 41.12 ± 0.39 |