Table 3. Coagulation and fibrinolysis laboratory variables, by Capnocytophaga canimorsus serovar and disease severity, Helsinki, Finland, 2000–2017*.
| Variable | Reference range | Serovar |
p value | Severity of illness |
p value | |||
|---|---|---|---|---|---|---|---|---|
| A, n = 17 | B, n = 28 | C, n = 22 | Severe, n = 25 | Mild, n = 45 | ||||
| Platelets, 109/L | 150–360 | 109 (29–137) [2] | 109 (28–140) [1] | 93 (23–166) [1] | 0.98 | 23 (9.5–89) [0] | 117 (95–154.3) [4] | <0.001 |
| PTT, %† | 70–130 | 56 (24–71) [10] | 78 (56–86) [11] | 58 (44.5–75) [12] | 0.284 | 54 (39–66) [2] | 87 (70.5–109.5) [31] | <0.001 |
| FiDD, mg/L | <0.5 | 47.9 (5.05–83.8) [12] | 9.1 (3.4–85.7) [19] | 14.5 (4.1–80.7) [15] | 0.888 | 32.9 (5.6–81) [5] | 1.6 (0.6–74.7) [40] | 0.057 |
*Values are given as median (interquartile range) [no. missing values] except as indicated. The comparison between patients with mild and severe courses of disease was defined by the level of care they needed. Patients with mild disease were those who were treated in a regular ward or the emergency department, and patients with severe disease were those treated in high surveillance or intensive care units. FiDD, fibrin D-dimers; PTT, partial thromboplastin time. †PTT was analyzed according to the Owren method (8). PTT was calculated as the ratio of the result (in seconds) from normal plasma to the result (in seconds) from the patient sample x 100.