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. 2018 Nov 20;9:940. doi: 10.3389/fneur.2018.00940

Table 3.

Subgroup analysis.

mRS 0–2 (vs. 3-6) at 3 months In-Hospital Mortality All-Cause Mortality (3 months) sICH
mRS 0–2, n (%) OR (95% CI); p* mRS 6, n (%) OR (95% CI); p mRS 6, n (%) OR (95% CI); p sICH yes, n (%) OR (95% CI); p
A: Etiology (Dissection, LAD, COMP)
Dissection 14 (53.8) 1.57 (0.69–3.59); 0.299 2 (7.7) 0.43 (0.10–1.92); 0.384 4 (15.4) 0.64 (0.21–1.97); 0.610 0 (n.a.) n.a.; 1.000
LAD 71 (47.7) 1.63 (0.90–2.97); 0.138 19 (12.8) 0.55 (0.26–1.19); 0.152 26 (17.4) 0.50 (0.25–0.98); 0.048 6 (4.1) 2.79 (0.33–23.87); 0.439
LAD/CE 10 (24.4) 0.34 (0.16–0.75); 0.005 12 (29.3) 3.03 (1.32–6.95); 0.014 16 (39.0) 3.09 (1.45–6.61); 0.005 1 (2.4) 0.70 (0.08–6.01); 1.000
mRS 02 (vs. 3–6) at 3 months In-Hospital Mortality All-Cause Mortality (3 months) sICH
mRS 0–2, n (%) OR (95% CI); p mRS 6, n (%) OR (95% CI); p mRS 6, n (%) OR (95% CI); p sICH yes, n (%) OR (95% CI); p
B: Loading (ticagrelor/aspirin vs. clopidogrel/aspirin)
Clopidogrel 37 (44.6) 1.04 (0.51–2.09); 0.920 9 (10.8) 0.46 (0.17–1.25); 0.129 14 (16.9) 0.75 (0.27–2.13); 0.594 0 (n.a.) n.a.; 0.048
Ticagrelor 62 (45.3) 24 (17.5) 32 (23.4) 7 (5.1)

LAD, large artery disease; LAD/CE, competing etiologies (LAD and cardiac embolism); mRS, modified Rankin Scale; OR, Odds ratio; CI, confidence interval; sICH, symptomatic intracranial hemorrhage; n.a., not applicable.

*

p-value for group comparison; outcome in one subgroup (e.g., dissection) vs. the remaining subgroups (LAD and LAD/CE).