Table 1.

Clinical data from the control and TLE patients^*.

		Control	TLE-HS1	TLE-HS2	p
Age** (years)		48 ± 15***	41 ± 11	40 ± 14	0.179a
Sex (male)		13 (92%)	9 (41%)	1 (50%)	0.008b
IPI age (years)		–	10 ± 9	3 ± 3	0.320c
IPI	No IPI	–	9 (41%)	1 (50%)	0.943b
	Febrile seizure	–	7 (32%)	1 (50%)
	Afebrile seizure	–	2 (9%)	0 (0%)
	TBI	–	2 (9%)	0 (0%)
	Meningitis	–	2 (9%)	0 (0%)
Seizure recurrence (years)		–	18 ± 12	10 ± 6	0.343d
Seizure frequency (monthly)		–	7 ± 10	17 ± 18	0.178c
Seizure generalization		–	10 (45%)	1 (50%)	0.902b
Seizures in clusters		–	13 (59%)	1 (50%)	0.803b
Status epilepticus (occurrence)		–	6 (27%)	1 (50%)	0.498b
Familiar history of epilepsy (positive)		–	13 (59%)	2 (100%)	0.253b
Surgical Outcome	ILAE1	–	14 (64%)	1 (50%)	0.742b
	ILAE2	–	2 (9%)	0 (0%)
	ILAE3	–	2 (9%)	0 (0%)
	ILAE4	–	3 (14%)	1 (50%)
	ILAE5	–	1 (4%)	0 (0%)
Other MRI findings	No other pathology	–	10 (45%)	1 (50%)	0.732b
	Cerebral/cerebellar atrophy		6 (27%)	0 (0%)
	Extratemporal calcification		2 (9%)	1 (50%)
	Diffuse microangiopathy		1 (4%)	0 (0%)
	Temporal pole blurring		2 (9%)	0 (0%)
	Gliotic lacunae in the Caudate		1 (4%)	0 (0%)
	Hypophysis hypertrophy		1 (4%)	0 (0%)

^*Only cases with high-resolution MRI are shown in this clinical table.

^**Age at surgery for TLE and age of death for controls.

^***Average ± standard deviation.

^aOne-way ANOVA.

^bExact test.

^cMann–Whitney test.

^dStudent's t-test.