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Function test of split-luc-HBcs
| Fusion protein | Luciferase function |
Signal intensity |
HBc function |
||
|---|---|---|---|---|---|
| Monomer interaction |
Capsid formation |
DNA replication |
|||
| FlucN-HBc | + | + | + | ND | + (weak) |
| FlucC-HBc | + | + | + | ND | + |
| RlucN-HBc | + | ++ | + | + | − |
| RlucC-HBc | + | ++ | + | + | + |
| GlucN-HBc | − | − | NDa | ND | ND |
| GlucC-HBc | − | − | ND | ND | ND |
| NlucN-HBc | + | +++ | + | ND | − |
| NlucC-HBc | + | +++ | + | ND | − |
ND, not determined.
