TABLE 1.

Percentage of C. botulinum type A strains inhibited across a range of MICs of 12 antimicrobial agents

Antimicrobial agent tested	Cumulative % C. botulinum type A strains (n = 156) with MIC (μg/ml)a of:
	≤0.50	≤1	≤2	≤4	≤8	≤16	≤32	≤64	≤128	≤256
AMCb	96	99	100
AMP	98.7	99.3					100c
PEN	99						100c
FEP	1	3	25	62	86	92	100
CTX	8	38	83	98	99	100
CRO	11	46	89	99	100
CXM	1	13	81	97	99	100
GEN							4	7	10	100
MXF	87	97	99	100
NAL					3	8	20	37	50	100
SXTd	65	71	76	78			100
VAN			2	8	61	97	99	100

^aMIC values determined by Etest method (AB Biodisk, Solna, Sweden).

^bConcentration represents the concentration of amoxicillin; amoxicillin and clavulanic acid were present at a ratio of 2/1.

^cA single highly resistant strain tested positive for beta-lactamase production by the chromogenic nitrocefin disk test (Hardy Diagnostics, Santa Maria, CA).

^dConcentration represents concentration of trimethoprim; trimethoprim and sulfamethoxazole were present at a ratio of 1/19.