Table 5.
Compound | L. major a |
---|---|
1 | 0.77 ± 0.09 |
2 | - |
3 | - |
4 | 0.65 ± 0.01 |
5 | - |
6 | 0.73 ±0.16 |
7 | - |
8 | - |
9 | 0.59 ± 0.07 |
10 | 0.61 ± 0.27 |
11 | - |
12 | 0.57 ±0.11 |
13 | 0.63 ± 0.04 |
14 | 0.68 ±0.12 |
15 | 0.66 ±0.18 |
16 | 0.81 ± 0.03 |
17 | 0.62 ± 0.08 |
18 | - |
Standard Drug IC50 (µg/mL± S.D) | |
Amphotericin B | 0.56 ± 0.20 |
a percentage inhibition activity: 100 = (non-significant; 0.95−0.80 = low; 0.79−0.70 = Moderate; 0.69−0.60 = Good; below 0.59-0.56 = Significant activity).