. 2010 Jan 12;15(1):288–304. doi: 10.3390/molecules15010288

Table 2.

IC₈₀ values related to PET inhibition in spinach chloroplasts in comparison with 3-(3,4-dichlorophenyl)-1,1-dimethylurea (DCMU) standard and in vitro antifungal activity (IC₈₀) of compounds 1-10, 12 and 14 compared with fluconazole (FLU) standard. (ND = not determined due to insufficient solubility of the compound).

Comp.	PET reductionIC₅₀ [ μmol/L]	MIC [µmol/L]
		CA^a	CT^a	CK^a	CG^a	TB^a	AF^b	AC^b	TM^b
		24h	24h	24h	24h	24h	24h	24h	72h
		48h	48h	48h	48h	48h	48h	48h	120h
1	78.0	>500	>500	>500	>500	>500	>500	>500	>500
1	78.0	>500	>500	>500	>500	>500	>500	>500	>500
2	ND	>250	>250	>250	>250	>250	>250	>250	>250
2	ND	>250	>250	>250	>250	>250	>250	>250	>250
3	33.5	0.77	1.95	3.90	1.95	3.90	0.77	7.80	1.95
3	33.5	1.95	3.90	3.90	3.90	3.90	1.95	7.80	1.95
4	ND	125	500	250	500	500	500	125	250
4	ND	500	500	500	500	500	500	250	250
5	54.4	125	250	250	125	250	250	125	62.50
5	54.4	250	250	250	250	500	250	125	125
6	304	125	125	125	125	125	125	125	125
6	304	125	125	125	125	125	125	125	125
7	616	>125	>125	>125	>125	>125	>125	>125	>125
7	616	>125	>125	>125	>125	>125	>125	>125	>125
8	306	15.60	31.25	62.50	31.25	62.50	62.50	62.50	62.50
8	306	62.50	31.25	62.50	62.50	125	62.50	62.50	62.50
9	ND	>125	>125	>125	>125	>125	125	62.50	62.50
9	ND	>125	>125	>125	>125	>125	125	125	62.50
10	660	125	125	125	125	125	125	31.25	15.62
10	660	>125	>125	>125	>125	>125	125	62.50	62.50
12	341	>125	>125	>125	>125	>125	125	62.50	15.62
12	341	>125	>125	>125	>125	>125	125	62.50	15.62
14	334	0.98	1.95	0.98	0.49	3.90	3.90	15.62	3.90
14	334	3.90	7.81	1.95	1.95	15.62	15.62	31.25	7.81
DCMU	1.9	–	–	–	–	–	–	–	–
FLU	–	0.06	0.12	3.91	0.98	0.24	>125	>125	1.95
FLU	–	0.12	>125	15.62	3.91	0.48	>125	>125	3.91

The MIC determination was performed according to the CLSI reference protocol: ^aM27-A2 for yeasts (IC₈₀ value) and ^bM38-A for moulds (IC₅₀ value).