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. 2018 Nov 27;73:e813s. doi: 10.6061/clinics/2018/e813s

Table 2. Cytotoxic selectivity index (SI), which represents the IC50 for PBMCs/cancer cell lines after 72h of treatment. PBMCs, peripheral blood mononuclear cells; SEM, standard error of the mean; IC50, the concentration of a compound needed to reduce cell growth by 50% in vitro.

Compound SI PBMC/HL-60 SI PBMC/OVCAR-8 SI PBMC/HCT-8
LASSBio-1920 333.30 11.11 20.0
LASSBio-1586 4.60 4.60 3.0
CA-4 1.45 6.40 0.60