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. 2018 Nov 20;9:2687. doi: 10.3389/fimmu.2018.02687

Figure 4.

Figure 4

Level of circulating anti-BP180 NC16A, but not anti-BP230 autoantibodies, measured by ELISA correlates with disease activity in patients with bullous pemphigoid. Relation of titers of circulating IgG anti-basement membrane zone autoantibodies, measured by indirect IF microscopy with disease activity: (A), ABSIS score of cutaneous involvement; (D), BPDAI global score (n = 75). Relation of titers of circulating IgG anti-BP180 NC16A autoantibodies, measured by ELISA with disease activity: (B), ABSIS score of cutaneous involvement; (E), BPDAI global score (n = 75). Relation of titers of circulating IgG anti-BP230 autoantibodies, measured by ELISA with disease activity: (C), ABSIS score of cutaneous involvement; (F), BPDAI global score (n = 75). The red line represents the locally weighted scatterplot smoothing line.