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. 2018 Nov 20;9:2687. doi: 10.3389/fimmu.2018.02687

Table 1.

Values of different clinical and immunopathological variables according to ELISA positivity (*).

Variable ELISA positive ELISA negative p-value
Age (years) (n = 82) 74.5 (68–80) (n = 8) 68 (60.5–74.25) 0.35
Indirect IF IgG 1,280 (400–2560) 640 (560–1600) 0.5
Complement-binding test 40 (10–140) 5 (4.25–6.25) < 0.001
Cryosection assay score 3 (3–4) 3 (2.75–3) 0.44
ABSIS cutaneous (n = 68) 40.25 (17.62–72.56) (n = 7) 9 (5.5–10) 0.01
BPDAI global score 53.5 (30–76.25) 11 (8–29) 0.007
BPDAI score of total skin involvement 49.5 (29.25–76.25) 11 (8–29) 0.009
BPDAI erosion activity 30 (20–49.25) 8 (6.5–26.5) 0.05
BPDAI urticaria/ erythema 12.5 (4–32.25) 2 (0–3) < 0.001
Mucosal involvement Yes (n = 11) No (n = 0) 0.58+
ESR (mm/h) (n = 66) 18.5 (11–32.75) (n = 7) 15 (12.5–28) 0.72

Mann-Whitney U test has been used.

+

Fisher Exact test has been used.

*

ELISA positivity is defined as presence of a level of anti-BP180 NC16A autoantibodies and/or anti-BP230 autoantibodies ≥ 9 U/mL.