Table 1.
Values of different clinical and immunopathological variables according to ELISA positivity (*).
Variable | ELISA positive | ELISA negative | p-value |
---|---|---|---|
Age (years) | (n = 82) 74.5 (68–80) | (n = 8) 68 (60.5–74.25) | 0.35• |
Indirect IF IgG | 1,280 (400–2560) | 640 (560–1600) | 0.5• |
Complement-binding test | 40 (10–140) | 5 (4.25–6.25) | < 0.001• |
Cryosection assay score | 3 (3–4) | 3 (2.75–3) | 0.44• |
ABSIS cutaneous | (n = 68) 40.25 (17.62–72.56) | (n = 7) 9 (5.5–10) | 0.01• |
BPDAI global score | 53.5 (30–76.25) | 11 (8–29) | 0.007• |
BPDAI score of total skin involvement | 49.5 (29.25–76.25) | 11 (8–29) | 0.009 |
BPDAI erosion activity | 30 (20–49.25) | 8 (6.5–26.5) | 0.05• |
BPDAI urticaria/ erythema | 12.5 (4–32.25) | 2 (0–3) | < 0.001• |
Mucosal involvement | Yes (n = 11) | No (n = 0) | 0.58+ |
ESR (mm/h) | (n = 66) 18.5 (11–32.75) | (n = 7) 15 (12.5–28) | 0.72• |
Mann-Whitney U test has been used.
Fisher Exact test has been used.
ELISA positivity is defined as presence of a level of anti-BP180 NC16A autoantibodies and/or anti-BP230 autoantibodies ≥ 9 U/mL.