Table 1.

Assessment of intraductal papillomas without atypia according to the upgrade status at excision. Distance to the nipple in mm was significantly greater in lesions with an upgrade at excision, while the other characteristics did not reach significance

	Overall (n = 62)	No upgrade (n = 52)	Upgrade (n = 10)	p value
Age, mean ± SD, years	54.7 ± 12.6	53.8 ± 12.6	59.7 ± 11.7	0.174
Menopausal status, n				0.871
Premenopausal	20	18	3
Peri-/postmenopausal	42	34	7
Tumor size
Mean ± SD, mm	11.5 ± 7.1	11.3 ± 7.0	12.3 ± 8.3	0.941
≥15 mm, n	15	9	2	1.000
<15 mm, n	47	43	8
Distance to nipplea, mean ± SD, mm	41.5 ± 27.6	36.8 ± 24.2	63.5 ± 32.8	0.012
Tumor characteristics, n				0.808
Mass	46	40	6
Non-mass	12	10	2
Architectural distortion	2	2	0
Micro calcifications, n				1.000
Yes	8	7	1
No	54	35	9
Initial BI-RADS category, n				0.805
BI-RADS 3	4	4	0
BI-RADS 4	54	46	8
BI-RADS 5	4	2	2
History of breast cancer in the contralateral breast, n				0.629
Yes	9	7	2
No	53	45	8
Biopsy procedure, n				1.000
CNB	48	40	8
VAB	14	12	2
Biopsy guidance, n				0.901
US	45	37	8
MG	12	10	2
MRI	5	5	0

^aDistance to the nipple in mm was significantly greater in lesions with an upgrade at excision, while the other characteristics did not reach significance.

SD = Standard deviation; CNB = core needle biopsy; VAB = vacuum-assisted biopsy; US = ultrasound; MG = mammography; MRI = magnetic resonance imaging.