Figure 5.
The four coagulation tests.
Notes: (A) TT results showed additive interaction between SiNPs and Pb(AC)2 (F=0.016, P=0.901); (B) FIB results showed additive interaction between SiNPs and Pb(AC)2 (F=0.369, P=0.550); (C) APTT results showed additive interaction between SiNPs and Pb(AC)2 (F=0.735, P=0.402), #P<0.05 when comparing co-exposure group with control group in APTT; (D) PT results showed additive interaction between SiNPs and Pb(AC)2 (F=0.018, P=0.895). Data are expressed as mean ± SD from six independent experiments. *P<0.05 compared with untreated control, #P<0.05 compared with individual toxicant alone treated group.
Abbreviations: APTT, activated partial thromboplastin time; FIB, human fibrinogen; Pb(AC)2, lead acetate; PT, prothrombin time; SiNPs, silica nanoparticles; TT, thrombin time.