Table 4.
Minor allele frequencies in our donor population compared to the non-Finnish European population in the ExAC database
| Antigen | dbSNP No. | Minor allele | MAF in our cohort | MAF in ExAC | Significance* |
|---|---|---|---|---|---|
| Blood groups | |||||
| S | rs7683365 | GYPB*c.143T | 0.3121 | 0.3802 | <0.001 |
| Lu(a) | rs28399653 | LU*c.230A | 0.0390 | 0.0382 | 0.935 |
| LU14 | rs28399656 | LU*c.611T | 0.0234 | 0.0146 | 0.048 |
| Au(b) | rs1135062 | LU*c.1615G | 0.2962 | 0.2993 | 0.809 |
| K | rs8176058 | KEL*c.578T | 0.0430 | 0.0412 | 0.753 |
| Kp(a) | rs8176059 | KEL*c.841T | 0.0091 | 0.0105 | 0.634 |
| Js(a) | rs8176038 | KEL*c.1790C | 0.0002 | 0.0005 | 0.548 |
| KEL17 | rs61729034 | KEL*c.905C | 0.0014 | 0.0018 | 0.726 |
| Fy(a) | rs12075 | FY*c.125G | 0.4325 | 0.4244 | 0.632 |
| Jk(b) | rs1058396 | SLC14A1*c.838A | 0.4897 | 0.4912 | 0.950 |
| Di(a) | rs2285644 | SLC4A1*c.2561T | 0.0005 | 0.0004 | 0.823 |
| Wr(a) | rs75731670 | SLC4A1*c.1972A | 0.0007 | 0.0002 | 0.114 |
| Yt(b) | rs1799805 | ACHE*c.1057A | 0.0597 | 0.0502 | 0.211 |
| Sc2 | rs56025238 | ERMAP*c.169A | 0.0036 | 0.0050 | 0.628 |
| Do(a) | rs11276 | ART4*c.793A | 0.4000 | 0.3849 | 0.348 |
| Co(b) | rs28362692 | AQP1*c.134T | 0.0372 | 0.0398 | 0.623 |
| LAN- | rs149202834 | ABCB6*c.574T | 0.0048 | 0.0030 | 0.454 |
| Platelet antigens (HPA) | |||||
| HPA-1b | rs5918 | ITGB3*c.176C | 0.1499 | 0.1553 | 0.629 |
| HPA-2b | rs6065 | GP1BA*c.482T | 0.0904 | 0.0865 | 0.697 |
| HPA-3b | rs5911 | ITGA2B*c.2621G | 0.3792 | 0.4443 | <0.001 |
| HPA-5b | rs1801106 | ITGA2*c.1600A | 0.0976 | 0.0918 | 0.553 |
| HPA-15a | rs10455097 | CD109*c.2108C | 0.4919 | 0.4975 | 0,752 |
| Neutrophil antigens (HNA) | |||||
| HNA-3b | rs2288904 | SLC44A2*c.461A | 0.2358 | 0.2094 | 0.048 |
| HNA-4b | rs1143679 | ITGAM*c.230A | 0.1095 | 0.1769 | <0.001 |
| HNA-5b | rs2230433 | ITGAL*c.2372C | 0.2879 | 0.2856 | 0.889 |
*
Bold numbers indicate significant differences (p < 0.05) of MAF between both populations.