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. 2018 Sep 19;16(6):4737–4744. doi: 10.3892/etm.2018.6770

Figure 2.

Figure 2.

Effect of the TNF-α inhibitor on the expression of inflammation-associated factors in synovial fibroblasts isolated from rats with osteoarthritis. (A) Levels of MMP-3, MMP-9, VEGF and ADAMTS4 expression in the synovial fibroblasts of rats with osteoarthritis and healthy rats, as determined by western blotting. (B) Levels of MMP-3, MMP-9, VEGF and ADAMTS4 expression in synovial fibroblasts taken from rats with osteoarthritis following treatment with TNF-α inhibitor or vehicle. Data are expressed as the mean ± standard deviation. **P<0.01. TNF-α, tumor necrosis factor α; MMP, matrix metalloproteinase; VEGF, vascular endothelial growth factor.