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. 2018 Aug 2;84(Suppl 1):30–45. doi: 10.1038/s41390-018-0080-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — The relationship between loading conditions and deformation parameters. There is a negative relationship between strain and systemic vascular resistance (a surrogate of afterload) but a positive relationship between strain and left ventricle end-diastolic diameter (a surrogate of preload). Note the lack of relationship between systolic strain rate and loading measures (data set from ref. ²⁶)