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Expression of HIF-1α, VEGF and VEGFR2 in COPD patients.
| VEGF, n (%) | VEGFR2, n (%) | ||||
|---|---|---|---|---|---|
| HIF-1α | Total n | (+) | (−) | (+) | (−) |
| (+) | 16 | 10 (62.5) | 6 (37.5) | 11 (68.8) | 5 (31.2) |
| (−) | 18 | 3 (16.7)a | 15 (83.3)a | 4 (22.2)a | 14 (77.8)a |
P<0.05 vs. HIF-1α (+). COPD, chronic obstructive pulmonary disease; HIF-1α, hypoxia-inducible factor-1; VEGF, vascular endothelial growth factor; VEGFR2, vascular endothelial growth factor receptor 2.
