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. 2018 Oct 1;2018(9):CD003968. doi: 10.1002/14651858.CD003968.pub5

Richter 1986.

Study characteristics
Methods RCT. 3 arms. Assessed at pretreatment, post‐treatment
Participants End of treatment: n = 43
Start of treatment: n = 51
Sex: 34 F, 17 M
Mean age = 12.9 years
Source = referred by physicians to children's hospital
Diagnosis = migraine
Mean years of pain = not given: mostly over 2 years
Interventions "Relaxation training"
"Cognitive coping"
"Attention control"
Outcomes Primary pain outcome: headache diary
Primary disability outcome: none
Primary depression outcome: Child Depression Rating Scale
Primary anxiety outcome: State Trait Anxiety Inventory
  1. Headache index (intensity, frequency, duration, medication taken: diary)

  2. State Trait Anxiety Inventory (STAI) or State‐Trait Anxiety Inventory for Children (STAI‐C)

  3. Children's Depression Rating Scale

Notes COI: not reported
Funding: "This research was supported by grants from the Ontario Ministry of Health and the Ontario Ministry of Community and Social Services."
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "... and randomly assigned to treatment"
Comment: probably done, no method described
Allocation concealment (selection bias) Unclear risk No description found in text
Comment: probably not done
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk No description found in text
Comment: probably not done
Incomplete outcome data (attrition bias)
All outcomes Low risk "Over the course of treatment there were 8 drop‐outs. A chi‐square analysis comparing attrition rates across interventions was not significant."
Comment: attrition adequately reported and no significant differences between completers and non‐completers reported
Selective reporting (reporting bias) High risk Data were incompletely reported