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. 2018 Oct 1;2018(9):CD003968. doi: 10.1002/14651858.CD003968.pub5

Van Tilburg 2009.

Study characteristics
Methods RCT. 2 arms. Assessed at pretreatment, post‐treatment, 6 months
Participants End of treatment: n = 29; follow‐up: n = 24
Start of treatment: n = 34
Sex: 25 F, 9 M
Mean age = 10.25 years (SD 2.6)
Source = University of North Carolina and Duke University Medical Centres
Diagnosis = functional abdominal pain
Mean years of pain = unknown
Interventions “Guided imagery treatment”
“Standard medical care”
Outcomes Primary pain outcome: Abdominal Pain Index
Primary disability outcome: Functional Disability Inventory
Primary depression outcome: none
Primary anxiety outcome: none
  1. Abdominal Pain Index

  2. Functional Disability Inventory

  3. School attendance

  4. Pediatric Quality of Life Inventory

  5. Global rating of change in abdominal pain

  6. Treatment compliance

  7. Questionnaire of paediatric gastrointestinal symptoms

  8. Healthcare utilisation

Notes COI: the authors indicated they had no financial relationships relevant to this article to disclose
Funding: this work was supported by National Institutes of Health grants R24 DK067674 and RR00046
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk “Thirty‐four children were assigned randomly
to receive 2 months of standard medical care with or without home‐based, guided imagery treatment.”
Comment: probably done, method not described
Allocation concealment (selection bias) Low risk “Children picked a closed envelope that determined whether they would receive standard medical care with or without guided imagery treatment.”
Comment: probably done
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk No description found in text
Comment: probably not done
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Attrition was described, however significant
differences between completers and non‐completers were not reported
Selective reporting (reporting bias) Unclear risk Data provided on request.