Figure 2.
SENP2 regulates OS cell proliferation, migration and invasion. (A) SENP2 protein expression in MG63 cells with or without Flag-SENP2 overexpression. (B) Cell growth curve, (C) migration assay and (D) invasion assay for Con-MG63 and Flag-SENP2-MG63 cells. (E) SENP2 protein expression in control or SENP2 KO cells. (F) Cell growth curve, (G) migration assay and (H) invasion assay for control and SENP2 KO Hos cells. **P<0.01 and ***P<0.005 vs. CON; ##P<0.01 and ###P<0.005 vs. WT. SENP2, small ubiquitin-like modifier-specific protease 2; OS, osteosarcoma; KO, knockout; WT, wild type; Con, control.
