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. 2010 Apr 13;15(4):2686–2718. doi: 10.3390/molecules15042686

Scheme 11.

Scheme 11

Synthesis of the 124I-labeled purpurinimide derivatives [124I]12, [124I]14 and [124I]16: a) (i) n-hexyl amine (ii) HBr/AcOH (iii) 3-Iodobenzyl alcohol; b) (i) 3-iodobenzyl amine (ii) HBr/AcOH (iii) R-OH; c) Sn2Me6, PdCl2(PPh3)2; d) Iodogen®, [124I]NaI.