Effect of Rab31 expression on proliferation, migration and invasion in ESCC Eca109 cells. (A) Proliferation of Eca109 cells following transfection with miR-NC, miR-455-5p mimics or miR-455-5p mimics + Rab31. *P<0.05 vs. miR-NC group and #P<0.05 vs. miR-455-5p mimics group. (B) Proliferation of Eca109 cells following transfection with miR-NC, miR-455-5p inhibitor or miR-455-5p inhibitor + shR-Rab31. *P<0.05 vs. miR-NC group and &P<0.05 vs. miR-455-5p inhibitor group. Cell proliferation was determined by using a Cell Counting Kit-8 assay. (C) Migration and invasion of Eca109 cells following transfection with miR-NC, miR-455-5p mimics or miR-455-5p mimics + Rab31. *P<0.05 vs. miR-NC group and #P<0.05 vs. miR-455-5p mimics group. (D) Migration and invasion of Eca109 cells following transfection with miR-NC, miR-455-5p inhibitor or miR-455-5p inhibitor + shR-Rab31. *P<0.05 vs. miR-NC group and &P<0.05 vs. miR-455-5p inhibitor group. ESCC, esophageal squamous cell carcinoma; miR, microRNA; NC, negative control.