Table 2.
Estimates of the impacts of LAIV pilot program during the 2014/2015 influenza season in individual pilot locations and supersets of them. For each area considered, the precampaign Pearson correlation r with chosen control areas, the mean and 95% confidence intervals of the absolute and relative mean impact δv and θv during the intervention period, the number of control areas chosen n(c), and the size of the population targeted in the chosen vaccination Pop(v) and control Pop(c) areas are presented. Statistically significant results are highlighted in italics.
|
Pilot area |
r a | δvb | θvc | n (c)d | Pop (v)e | Pop (c)f |
| All vaccinated | 0.89 | -0.50 (-2.77 to 1.99) | -4.51 (-25.72 to 22.61) | 10 | 9,772,977 | 5,066,069 |
| All “Primary school” | 0.71 | -1.15 (-2.19 to -0.15) | -16.97 (-30.09 to -2.42) | 8 | 2,719,231 | 2,371,367 |
| All “Primary and Secondary school” | 0.84 | -0.06 (-1.50 to 1.43) | -0.30 (-16.71 to 19.36) | 6 | 1,097,419 | 2,174,854 |
| All “Primary school” and “Primary and Secondary school” | 0.85 | -1.35 (-3.37 to 0.66) | -13.01 (-30.54 to 7.31) | 9 | 4,062,624 | 3,601,377 |
| All “Secondary school” | 0.83 | 0.06 (-1.58 to 1.90) | 1.41 (-19.40 to 28.40) | 7 | 5,710,353 | 4,038,921 |
| Cumbria (“Primary school”) | 0.59 | 0.04 (-0.24 to 0.33) | 1.07 (-5.75 to 8.17) | 7 | 497,874 | 3,999,608 |
| Essex (“Primary school”) | 0.68 | -0.32 (-1.13 to 0.51) | -5.91 (-20.56 to 10.58) | 8 | 1,431,953 | 3,199,730 |
| Gateshead (“Primary school”) | 0.59 | -0.39 (-0.74 to -0.04) | -8.46 (-15.56 to -1.02) | 4 | 200,505 | 1,551,060 |
| South Tyneside (“Primary school”) | 0.34 | 0.25 (0.03 to 0.52) | 6.82 (0.81 to 14.07) | 3 | 148,740 | 1,697,971 |
| Sunderland (“Primary school”) | 0.54 | 0.12 (-0.05 to 0.32) | 3.20 (-1.38 to 8.38) | 3 | 276,889 | 1,119,136 |
| Thurrock (“Primary school”) | 0.32 | 0.04 (-0.14 to 0.23) | 1.01 (-3.56 to 6.24) | 3 | 163,270 | 753,563 |
| Bury (“Primary and Secondary school”) | 0.32 | -0.11 (-0.37 to 0.12) | -2.60 (-8.94 to 3.13) | 2 | 187,474 | 893,813 |
| Leicestershire (“Primary and Secondary school”) | 0.81 | 0.32 (-0.70 to 1.38) | 4.97 (-10.01 to 21.22) | 6 | 667,905 | 2,756,865 |
| Salford (“Primary and Secondary school”) | 0.67 | 0.40 (-0.20 to 1.01) | 8.45 (-3.96 to 22.00) | 7 | 242,040 | 4,183,184 |
| Havering (“Primary and Secondary school”-year 7) | 0.48 | -0.03 (-0.35 to 0.31) | -0.55 (-8.23 to 7.79) | 4 | 245,974 | 1,742,705 |
| Birmingham (“Secondary school”) | 0.79 | 0.53 (-0.27 to 1.34) | 10.36 (-4.86 to 27.21) | 10 | 1,101,360 | 5,435,742 |
| Lancashire (“Secondary school”) | 0.65 | 0.18 (-0.78 to 1.13) | 3.45 (-13.41 to 21.40) | 8 | 1,184,735 | 3,463,060 |
| Leeds (“Secondary school”) | 0.63 | 0.54 (-0.40 to 1.51) | 10.81 (-7.41 to 30.98) | 7 | 766,399 | 2,731,293 |
| Lincolnshire (“Secondary school”) | 0.66 | -0.29 (-0.78 to 0.19) | -6.09 (-16.20 to 4.25) | 6 | 731,516 | 1,737,168 |
| Norfolk (“Secondary school”) | 0.71 | -0.12 (-0.60 to 0.35) | -2.31 (-11.55 to 7.25) | 6 | 877,710 | 2,784,394 |
| Shropshire (“Secondary school”) | 0.35 | 0.13 (-0.13 to 0.39) | 3.30 (-3.18 to 9.71) | 6 | 310,121 | 2,833,659 |
| Suffolk (“Secondary school”) | 0.59 | 0.10 (-0.34 to 0.53) | 2.24 (-7.54 to 12.35) | 5 | 738,512 | 2,015,339 |
ar: The precampaign Pearson correlation with the chosen aggregation of control areas
bδv: The absolute difference in the mean ILI rate during the intervention period
cθv: The relative difference in the mean ILI rate during the intervention period
dn (c): The number of aggregated control areas chosen
ePop (v): The size of the population targeted in the chosen vaccination areas
fPop (c): The size of the population targeted in the chosen aggregation of control areas